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They must either have: BMI of at least 35 BMI of at least 30 plus a history of heart failure, uncontrolled hypertension or chronic kidney disease BMI of at least 27 plus prediabetes, a previous heart attack or stroke, or symptomatic peripheral artery disease
To ensure patient confidentiality, only the main physician of the patients would review their files for the information of interest and would add de-identified patient data to the form
For the cerebrovascular uptake study ( n = 22), male and female homozygous APOE2-, APOE3-, and APOE4-TR mice were euthanized at 26-weeks (Supplementary Table S2)
It was established that carboxyethylpyrrole (a LPO product) induces retinal infiltration of macrophages, a pathological process that is blocked by the immunosuppressive therapy of CD4+ T cells (specifically Th1 and Th17 cells) (57)
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